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This thesis presents a new technique, Transient Induced Molecular Electronic Spectroscopy (TIMES), to study biomolecular interaction without protein engineering
Label-Free Technologies For Drug Discovery
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Over the past two decades the benefits of label-free biosensor analysis have begun to make an impact in the market, and systems are beginning to be used as main
Novel Kinetic Solution-Based Separation Approaches for Small Molecule Drug Discovery
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The modern pharmaceutical industry has achieved remarkable successes in medicinal chemistry. However, many diseases are incurable due to the difficulty of findi
Protein-Ligand Interactions
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The lock-and-key principle formulated by Emil Fischer as early as the end of the 19th century has still not lost any of its significance for the life sciences.
Activity-Based Protein Profiling
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This volume provides a collection of contemporary perspectives on using activity-based protein profiling (ABPP) for biological discoveries in protein science, m