Related Books

OECD Guidelines for the Testing of Chemicals, Section 2 Test No. 251: Rapid Androgen Disruption Activity Reporter (RADAR) assay
Language: en
Pages: 44
Authors: OECD
Categories:
Type: BOOK - Published: 2022-06-30 - Publisher: OECD Publishing

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The Rapid Androgen Disruption Activity Reporter (RADAR) Test Guideline describes an aquatic assay that utilizes transgenic Oryzias latipes (O. latipes, Japanese
OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 458: Stably Transfected Human Androgen Receptor Transcriptional Activation Assay for Detection of Androgenic Agonist and Antagonist Activity of Chemicals
Language: en
Pages: 84
Authors: OECD
Categories:
Type: BOOK - Published: 2023-07-04 - Publisher: OECD Publishing

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This Test Guideline describes in vitro assays, which use Androgen Receptor TransActivation (ARTA) to detect Androgen Receptor Agonists and Antagonists. The ARTA
OECD Guidelines for the Testing of Chemicals, Section 2 Test No. 250: EASZY assay - Detection of Endocrine Active Substances, acting through estrogen receptors, using transgenic tg(cyp19a1b:GFP) Zebrafish embrYos
Language: en
Pages: 45
Authors: OECD
Categories:
Type: BOOK - Published: 2021-06-17 - Publisher: OECD Publishing

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The EASZY assay is a mechanism-based in vivo screening assay designed to detect endocrine active chemicals acting as agonist through estrogen receptors (ERs), b
OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 455: Performance-Based Test Guideline for Stably Transfected Transactivation In Vitro Assays to Detect Estrogen Receptor Agonists and Antagonists
Language: en
Pages: 74
Authors: OECD
Categories:
Type: BOOK - Published: 2021-06-17 - Publisher: OECD Publishing

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This Performance-Based Test Guideline (PBTG) describes in vitro assays, which provide the methodology of Stably Transfected Transactivation to detect Estrogen R
OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 456: H295R Steroidogenesis Assay
Language: en
Pages: 27
Authors: OECD
Categories:
Type: BOOK - Published: 2011-07-28 - Publisher: OECD Publishing

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This Test Guideline describes an in vitro screen for chemical effects on steroidogenesis, specifically the production of 17ß-estradiol (E2) and testosterone (T