Download or read book Mechanisms of Lymphocyte Activation and Immune Regulation XI written by Sudhir Gupta and published by Springer Science & Business Media. This book was released on 2007-05-21 with total page 197 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, major developments have increased understanding of various genetic and epigenetic regulatory processes that are critical for the generation of B cell repertoires. These include the role of chromatin regulation and nuclear organization in understating the IgH gene regulation. These proceedings highlight recent developments in lymphocyte development, Ig gene rearrangements and somatic hypermutation, chromatin structure modification, B lymphocyte signaling and fate, receptor editing, and autoimmunity.