The book focuses on protein allostery in drug discovery. Allosteric regulation, ʹthe second secret of lifeʹ, fine-tunes virtually most biological processes an
Although the concept of allosterism has been known for over half a century, its application in drug discovery has exploded in recent years. The emergence of nov
With the most comprehensive and up-to-date overview of structure-based drug discovery covering both experimental and computational approaches, Structural Biolog
Detailed characterization of fuzzy interactions will be of central importance for understanding the diverse biological functions of intrinsically disordered pro
A guide to applying the power of modern simulation tools to better drug design Biomolecular Simulations in Structure-based Drug Discovery offers an up-to-date a