The zinc metalloproteases are a diverse group of enzymes which are becoming increasingly important in a variety of biological systems. Their major function is t
This study covers the sequence information, three-dimensional structures, activation, protein substrates, specificity requirements, inhibition, and biological r
Over the last decades cell biology and biological chemistry have increasingly turned their attention to the space between cells and revealed an elaborate networ
Matrix metalloproteinases (MMPs) are members of an enzyme family and are critical for maintaining tissue allostasis. MMPs can catalyze normal turnover of the ex
Abnormal metabolism and distribution of both copper and zinc occurs in many inflammatory and degenerative diseases. The pattern of these changes varies at diffe